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doi: 10.1073/pnas.1301816110 39

It governs facility design, equipment qualification, batch records, and release testing for drug-destined compounds

Additionally, manual liver compression and massage are all practices to aid the organ that is our liver.

Altogether, these observations suggest that ADC-triggered lactate and ROS release would favour the establishment of an overall immunosuppressive TME that could contribute to tumour resistance to DXd-based ADC treatment