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The brain must generate large amounts of ATP to maintain the membrane potential, which is essential for the transmission of nerve impulses

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Among the phosphosites, S908 is part of a recognition motif for PKA-like kinases called the RRAS motif (or dibasic consensus sequence) and displays a similar conformation to that of a phosphomimetic peptide bound to PKA (PDB ID: 1ATP 29 )

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