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There is a study published in #ScienceDirect in August 2024 (A pilot study) concluded that B12 bioavailability reduced significantly from baseline (C) when metformin (M) was administered and this reduction was reversed when calcium was co-administered (MC) in healthy participants

Vitamin B12 is a water-soluble vitamin that plays an important role in red blood cell formation, cell metabolism, nerve function, and even the production of DNA

Inflammation Chronic inflammation, metabolic syndrome, and liver disease can also lower glutathione levels (GSH levels), leaving your bodys cells more vulnerable to damage

Sections were incubated with primary antibodies in PBS overnight at 4 C for immunohistochemistry

PMID: 39923835 Mol Cell Proteomics 2026 Apr 28:101573