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Not saying breast cancer is always the case

Metabolic and nonmetabolic functions of PSAT1 coordinate signaling cascades to confer EGFR inhibitor resistance and drive progression in lung adenocarcinoma

BalabanNQHelaineSLewisKAckermannMAldridgeBAnderssonDIet al

Structural analyses reveal tight interactions between L-phosphoserines phosphate group and conserved arginine (Arg42, Arg328) and histidine (His41, His327) residues, suggesting that analogs targeting these residues could yield potent inhibitors (77)