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We find that OTUD5 is cooperatively modified by TRIP12 and UBR5 to assemble K29/K48 branched ubiquitin chains

Where the antibody, polypeptide, peptide or fusion protein or fragment thereof (e.g., a biologically active fragment thereof) is recombinantly produced, it is also preferably substantially free of culture medium, i.e., culture medium comprises less than about 20%, more preferably less than about 10%, and most preferably less than about 5% of the volume of the protein preparation

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