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P.KumarK.KumarS.SinghK

Studies have shown that LicoE prevents dopaminergic neuronal degeneration by upregulating the Nrf2/ARE pathway and inhibiting M1 microglia-induced inflammatory responses (Kim et al., 2012)

Heuser C, Renner K, Kreutz M, Gattinoni L

These studies indicate that while these supplements can offer benefits, they may also have detrimental effects on kidney function in certain individuals

Daily intake of carbon tetrachloride for long-term exposure of the general population Prevailing upper limits Worst case scenario Concentration Daily intake Concentration Daily intake Air 1 g/m 3 1 g/m 3 22 m 3 0.4 a = 8.8 g 9 g/m 3 9 g/m 3 22 m 3 0.4 a = 79.2 g Water 0.1 g/litre 0.1 g/litre 2 litres = 0.2 g 16 g/litre 16 g/litres 2 litres = 32 g Food 3 g/kg 3 g/kg 1.5 kg = 4.5 g 31 g/kg 31 g/kg 1.5 kg = 46.5 g Total daily intake 13.5 g 157 g Total daily intake per kg 0.2 g 2.5 g body weight a The value of 0.4 derives from the 40% retention reported by ATSDR (1994) Carbon tetrachloride is of low toxicity to the algae and microorganisms tested