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1 Introduction Systemic lupus erythematosus (SLE) is a multifaceted autoimmune disorder that includes loss of tolerance to self-antigen and subsequent activation of autoreactive T and B cells, production of dysregulated cytokines ( The available treatment methods in SLE are chiefly immunosuppressants

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BPS Publications bpspubs.onlinelibrary.wiley.com To view or add a comment, sign in Methylene Blue in Clinical Practice: From FDA-Approved Methemoglobinemia Reversal to Off-Label Applications, Serotonergic Risks, and Safety --- -- -- Dr Indunil Karunarathna Uva Clinical Research Lab 2026 Uva Clinical Anaesthesia and Intensive Care ISSN 2827-7198, 2026 Methylene blue (methylthioninium chloride) DOI:10.5281/zenodo.20674932 is a century-old synthetic thiazine dye with a distinctive pharmacodynamic profile that encompasses redox cycling, alternative electron transport, and enzymatic inhibition

Genetic material is injected directly into the fertilized egg which is then implanted back into a mouse and allowed to come to term