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Description

We observed that BCL-2 mRNA was commonly and exclusively upregulated in castration-resistant (primary CRPC), castration/Enza-resistant (2 CRPC) and AR-knockout (ARKO) LNCaP models as well as in AR -/lo LAPC9 CRPC 20 (Fig

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PMC, NIH

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Interestingly, vitamin B-12 deficiencies are believed to be a major driver of a dysfunctional methylation cycle as evidenced by an association between homocysteine levels and vitamin B-12 deficiency (8)

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