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Although not documented in Keshan disease, it is possible that selenium deficiency may increase the virulence of viruses with the potential to invade and damage the heart muscle (57)

The endocon is in general supplied by a cofactor (a coenzyme or co-substrate) where a high-energy chemical bond links the cofactor to the endocon

PRDX6 is recruited to the peroxidized cell membrane after oxidative stress, where it reduces and hydrolyzes the oxidized sn-2 fatty acyl or the sn-2 ester (alkyl) bond of oxidized phospholipids

Onset of the condition can occur rapidly