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1.2 Distinctive contribution of the present review Several previously published reviews have summarized the biological activities of natural compounds and dietary supplements in breast cancer

Histone lactylation plays a role in regulating inflammation, tumorigenesis, nerve diseases, and muscle development by facilitating gene expression 20,23,24,25

ONeill CH, Scoggins CR

Trying to reduce the oxidative stress present, they used antioxidants like NAC (increase glutathione), metformin (increase SOD2 expression), and liproxstatin-1 (reduce lipid peroxide levels) in cell cultures and found that NAC and metformin was able to reduce immune activity to some extent