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However, the bioavailability of orally ingested peptides may limit factor in their effectiveness on the skin [74], as they must undergo digestion, absorption, and transport before reaching the target tissues

found that while macaques immunized with a modified vaccinia Ankara viral vector expressing the SARS-CoV S protein had reduced viral replication after challenge, anti-S IgG also enhanced pulmonary infiltration of inflammatory macrophages and resulted in more severe lung injury compared to unvaccinated animals 66

A., Mohd Faik, A

B., Yang, Y., Xu, X

The disease activity index was calculated by assigning well-established and validated scores