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Furthermore, leveraging this foundation to discover novel therapeutic gaseous mediators represents a critical research imperative

Acceptability of psychosocial interventions for dementia caregivers: a systematic review

In some embodiments, the polynucleotide that has a modulatory effect on an immune response is obtained by: (1) reassembling (&/or subjecting to one or more directed evolution methods described herein) at least first and second forms of a nucleic acid that is, or encodes a molecule that is, involved in modulating an immune response, wherein the first and second forms differ from each other in two or more nucleotides, to produce a library of experimentally generated (in vitro &/or in vivo) polynucleotides

doi:10.5812/asjsm.24898 10

For instance, AARS1-mediated lactylation of p53 at lysines 120 and 139 suppresses the transcription of p21, and p53 upregulates modulator of apoptosis (PUMA) by disrupting p53 LLPS and its DNA-binding capability