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For example, stretching or tensile strain can cause ERK activation, which leads to Madin Darby canine kidney epithelial cell (MDCK) contraction, propagation of the ERK signal in neighboring cells, and collective cell migration (184)

One notable finding from meta-analyses: cagrilintide demonstrated the lowest odds ratios for nausea, vomiting, and diarrhea when compared to other incretin-based therapies including semaglutide and tirzepatide

Researchers should understand both the available data and its limitations