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Approximately 30% of individuals with these mutations develop pulmonary hypertension [69, 70]

Selley ML, Bartlett MR, Czeti AL, Ardlie NG

CaDH mito activation of the Krebs cycle results in increased NADH production, which is critical to supply reducing equivalents for the electron transport chain (ETC), free radical (ROS) regulation and redox signalling 5

Faron-Grecka, A

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