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doi: 10.1080/17474086.2016.1254546 119 Seghal KiranG.PriyadharshiniS.DobsonA

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Like basal-like tumours, it is triple negative (ER-, PR-, HER2-) but differs in having low Ki67 expression and elevated markers associated with epithelial-mesenchymal transition, indicating a distinct biological behaviour (142, 143)

A cold-adapted tyrosinase with an abnormally high monophenolase/diphenolase activity ratio originating from the marine archaeon Candidatus Nitrosopumilus koreensis

They also participate in endogenous cellular metabolism [13] by functioning as glutathione peroxidases (GPOXs) that counteract oxidative stress, as flavonoid-binding proteins [7], as stress-signalling proteins [14], and in regulating apoptosis [15]