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16 HongJ

Nicolas-Avila JA, Adrover JM, Hidalgo A

Pause and Reassess When Symptoms are worsening progressively without any improvement trend

4-HNE is a byproduct of lipid peroxidation that can alter protein functions by forming 4-HNE-protein adducts, induce DNA damage, and act as a signaling inducer ( via apoptosis caused by accumulating 4-HNE