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Amyloid deposition, neurodegeneration, and cognitive decline in sporadic Alzheimers disease: a prospective cohort study

Eumelanin to Pheomelanin: Glutathione converts darker eumelanin to lighter pheomelanin, lightening skin

This metabolic shunting requires the substrate to reorient itself within the CYP binding site to offer an alternative position to the heme center for metabolism