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For example, in USP38-TG diabetic mice, pharmacological inhibition of RAGE with FPS-ZM1 attenuated cardiac systolic and diastolic dysfunction by improving LVEF, LVFS, and E/A ratio, reduced myocardial fibrosis, enhanced cardiac electrical stability, and suppressed inflammatory marker expression [166]

[DOI] [PMC free article] [PubMed] [Google Scholar] 27.Lee J.V., Carrer A., Shah S., Snyder N.W., Wei S., Venneti S., Worth A.J., Yuan Z.-F., Lim H.-W., Liu S., et al

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