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37 , 355.e21355.e29 (2019)

BHB binds directly to hydroxycarboxylic acid receptor 2 (HCA2) (also called GPR109A) on adipocytes (44)

If you are unfortunate enough to relapse after therapy, the use of an oral antibiotic for a short duration (8 weeks) combined with sustained retinoid therapy can sometimes calm down the breakout and help us avoid repeating a course of isotretinoin