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Prompt medical attention is essential if unusual tingling, weakness, or neuropathic pain is experienced in the hands or feet, as early diagnosis and treatment are crucial for symptom control and preventing further peripheral nerve damage

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The aim of this study was to prove our hypothesis that A-GSH functionalization increases brain endothelial internalization and BBB permeability of polymeric nanoparticles coupled with active agents, namely dopamine and ibuprofen, which have low brain penetration