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This matters more than most people realize

Cautious use is warranted for patients with other types of GI disease such as inflammatory bowel disease (ulcerative colitis, Crohns disease), as these conditions may be exacerbated

Many patients report feeling a sense of relaxation and calm, with some even experiencing a mild euphoria due to the rapid absorption of nutrients

Most people find this to be uncomfortable, but not unbearable, and it dramatically impacts the results you get - so its a tradeoff most people are willing to make

The study population characteristics were: median age of 64 years (range: 34 to 84), 49% age 65 years or older, 59% male, 94% White and 3% Asian, and 18% with history of brain metastases at baseline