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10.1016/j.chom.2023.01.011 387 SampsonT

"I think it's pretty good," he said of the opportunities

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It not only eliminates ROS, enhances SOD and GSH-Px activity, and reduces malondialdehyde (MDA) levels (33), but also inhibits the TLR4-mediated MyD88 cascade, decreases p65 nuclear translocation and downstream inflammatory factors, and simultaneously activates the PI3K/Akt pathway, increasing the Bcl-2/Bax ratio and inhibiting caspase-3-mediated apoptosis (23)