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The arginate modification is intended to improve the peptides stability and bioavailability, which may allow for more consistent delivery in the context of a wellness routine

doi: 10.1038/s41420-019-0146-x 75 SaccoABattagliaAMBottaCAversaIMancusoSCostanzoFet al

Interestingly, transgenic mice overexpressing SOD1 exhibited greater resistance to corticosterone-induced depressive-like behaviors compared to wild-type animals (104)

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These drawbacks point to the fact that alternative or complementary therapies that are safe and can regulate various pathological pathways are needed