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Truth Signs and Symptoms of a B12 Deficiency: Fatigue or weakness Brain fog or memory problems Tingling in hands and feet (neuropathy) Mood changes, irritability, or depression Pale or jaundiced skin Glossitis (a swollen, inflamed tongue) Dizziness or shortness of breath Visual disturbances If youve been dealing with any combination of these symptoms, its worth looking into your B12 status