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Melatonin modulates IL-1-induced extracellular matrix remodeling in human nucleus pulposus cells and attenuates rat intervertebral disc degeneration and inflammation

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227 In Cu-deficient mice, lipids are deposited in the myocardial tissue, with cardiac hypertrophy, mitochondrial swelling, and a blunted response to the isoproterenol, an agonist of beta-adrenergic