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These tumors display sparse T cell infiltration and low antigen presentation capacity, and are dominated by myeloid-derived suppressor cells (MDSCs) and Tregs

Despite conflicting observations, we have presented in this review, we believe we have highlighted substantial evidence to consider drug-induced mitochondrial toxicity as a risk factor for developing insulin resistance

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365,366 In most cases, it plays a predominant role in zinc accumulation in benign prostatic hyperplastic epithelial cells

Despite the encouraging advances in therapeutic development, further research is urgently needed to establish more personalized and accessible treatment paradigms for MASLD in the near future [95]