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Validation of these transcriptional shifts by RT-qPCR indicates that GR knockout leads to the strategic reconfiguration of metabolic and regulatory pathways in the bacterium

Trends Cancer 8:190209 Nosalova N, Keselakova A, Kello M, Martinkova M, Fabianova D, Pilatova MB (2023) Involvement of both extrinsic and intrinsic apoptotic pathways in Tridecylpyrrolidine-Diol Derivative-Induced apoptosis in Vitro

New York: Plenum Press.3751 44

Thus, ferroptosis can be defined as a non-apoptotic mode of regulated cell death, driven by iron accumulation and membrane lipid peroxidation when GPX4 activity is inhibited (Fig