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doi: 10.1111/j.1530-0277.2006.00195.x

Inorganic Chem Commun 3(9):453457

The body needs time to adapt to the dual GIP and GLP-1 receptor activation, and jumping to a higher dose invites unnecessary side effects

Additionally, NRH, the reduced form of nicotinamide ribose (NR), ameliorated aminoglycoside-induced hearing loss and attenuated HC damage by increasing NAD + levels and activating SIRT1 in the cochlea [117]