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Therefore, this narrative review navigates into the intricate role of TRP metabolism in insomnia and its psychological and neurological comorbidities, particularly cognitive dysfunction, depression, anxiety, stress, traumatic brain injury (TBI), chronic pain, and substance abuse

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The combination of reduced injection frequency plus consistent topical use maintains results efficiently

In the STEP 1 trial, Semaglutide 2.4 mg weekly produced an average weight loss of 14.9% at 68 weeks, versus 2.4% with placebo (Wilding et al., NEJM 2021

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