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We used linear mixed-effects models to test associations between long-term change in VD, and MD, stroke subtype (i.e., cortical, lacunar, or cerebellum), and temporal change in infarct volume, adjusted for age, time after stroke, National Institutes of Health Stroke Scale score, smoking history, hypertension, diabetes, total cholesterol, eye laterality, ocular pathology, and OCTA image quality

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To make the nanomaterials reach clinical trial and for long-term and sustainable use, simplified formulations must be adapted, and a thorough toxicity profile of the synthesized nanomaterials must be performed for the long term

Proc Natl Acad Sci USA 94: 59238 pmid:9159176 22

& Carter-Su, C