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Hypothetically, this drop in demyelination might circumvent the loss of fatty acid degradation by astrocytes as a trigger for neurodegeneration [60]

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Following IM administration of atropine in one study, elimination of the drug (determined by urinary excretion of radiolabeled drug) appeared to be biphasic, with a half-life in the initial phase of about 2 hours and a half-life in the terminal phase of 12.5 hours or longer

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Dose-response relationships: Biological effects show threshold (minimum effective concentration), linear response zone (increasing dose produces proportional benefits), and saturation (maximum benefit reached, further increases provide minimal additional effect)