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Those trials have methodological limitations (small, often open-label, in Russian journals), but they exist

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Patients often start with an intensive "loading phase," which can mean daily or every-other-day injections for a week, then weekly shots for a month

Patients are advised to report any unexpected symptoms to their healthcare provider, and clinicians will typically monitor for symptoms of hypoglycemia or gastrointestinal upset during therapy

Read more from Gray's Compounding Pharmacy: Part 1: The story of progesterone Part 3: Hormones and women's health Part 4: The story of Testosterone