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Some writers have proposed that this dietary transition supported evolutionary selection for significant physiologic and anatomic changes in Homo , such as increase of the brain size and reduced gut volume (Aiello and Wheeler, 1995

American Diabetes Association (2003)

This reaction takes place in the mitochondrial matrix and is catalyzed by carnitine acyltransferase 2 (also called carnitine palmitoyltransferase 2, CPT2), which is located on the inner face of the inner mitochondrial membrane