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Our findings demonstrated that GSH inhibition leads to synthetic lethality in VRK2-deficient PC cells, which exhibits impaired expression of SLC7A11 at PM level

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In this review, Carr and Cook reported that VitC administration typically decreases white blood cell loss, weight loss, ascites accumulation, hepatotoxicity, reticulocytosis, lipid oxidation and cardiomyopathy induced by the chemotherapeutic agents