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The RCDs exhibit superior photothermal efficiency compared to the ECDs in ERCD-1 (ECD:RCD = 1:2.5), allowing NIR irradiation to preferentially heat the RCD region

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This is because myelination needs energy and nutrition, and any systemic (respiratory or cardiac) or neurologic disease such as meningoencephalitis during the initial 1824 months of age can delay myelination, and the child can later catch up with myelination

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