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The doses used in neurological models in animals fall within the same general range as musculoskeletal studies, suggesting that a standard subcutaneous protocol at 250 to 500 micrograms per day would be the appropriate starting framework

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Check vitamin B12 levels in people treated with metformin who have symptoms suggestive of vitamin B12 deficiency This will also include patients found to have megaloblastic anaemia (raised mean corpuscular volume [MVC]), who may be asymptomatic (MHRA, 2022)

There are two PAS support groups in USA