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If your B12 level is normal to high, adding more B12 will not make you feel any better or aid in weight loss

Medical conditions affecting absorption warrant particular attention : Pernicious anaemia : an autoimmune condition destroying gastric parietal cells, requiring lifelong B12 injections Gastrointestinal surgery : particularly gastric bypass, gastrectomy, or terminal ileum resection Inflammatory bowel disease : Crohn's disease affecting the terminal ileum impairs absorption Coeliac disease : untreated disease damages the small intestine, reducing B12 uptake Medication use : long-term metformin therapy (MHRA safety alert) or nitrous oxide exposure Symptoms suggesting possible B12 deficiency include : persistent fatigue, weakness, paraesthesia (pins and needles) in hands or feet, glossitis (sore, red tongue), mood changes, memory problems, or unexplained anaemia

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All products are strictly for laboratory research and are not for human or veterinary use

IMR-5/75-shMYCN and SH-SY5Y/6TR(EU)/pTrex-Dest-30/MYCN are named IMR-5/75 and SH-SY5Y/MYCN, respectively, in this paper