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Considering CO23FLC strain with respect to the sensitive one we observed an increase of intracellular level of GSH that may be due either to a stimulated biosynthesis of this compound or to a major activity of glutathione reductase able to revert the GSSG form to GSH

10.1093/ajcn/nqab299 Am J Clin Nutr

4.4 Summary of the integrated testicular-penile pathological axis The mechanisms described above suggest that varicocele may contribute to ED through a multi-level testicularpenile pathological axis centered on inflammation, oxidative stress, vascular dysfunction, smooth muscle remodeling, and neural injury (111)

This elevation was due to increased GSH content and decreased GSSG content after Sal A treatment