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A randomized controlled study demonstrated that acupuncture combined with methylcobalamin is more effective in treating BIPN than methylcobalamin alone (Moore et al., 2020)

Meanwhile, Lee N et al

Qu et al., 2023

IM administration provides faster absorption

Associations with polymorphisms in genes encoding UGT1A1, UGT1A6, UGT1A9, UGT2B15, and SULT1A1 were not detected in the same patient populations [100]