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Harmful effects of ONOO are varied including oxidation of macromolecules (DNA, proteins, lipids), nitration of amino acids and inactivating mitochondrial enzymes leading to mitochondrial dysfunction

[DOI] [PubMed] [Google Scholar] 65.Stambolija V., Stambolija T.P., Holjevac J.K., Murselovic T., Radonic J., Duzel V., Duplancic B., Uzun S., Zivanovic-Posilovic G., Kolenc D., et al

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The resin sections were taken at a 0.5 m thickness and stained with toluidine blue

They found that metabolic derangements were associated with increased risk of mortality in both moderate and severe TBI clusters