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RBCs use the cofactor S-adenosyl-homocysteine (SAM) and Protein-L-isoaspartate O-methyltransferase (PCMT1) system, to repair proteins damaged by oxidative stress 49

*Compared to absorption through the skin

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Intratracheal budesonide-poly(lactide-co-glycolide) microparticles reduce oxidative stress, VEGF expression, and vascular leakage in a benzo(a)pyrene-fed mouse model