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However, unregulated use or incorrect dosage may lead to health concerns in some cases

However, in pathological states, such as during reperfusion, the generation of ROS from the electron transport chain (ETC), particularly complexes I and III, exceeds the normal resulting in leakage of electrons that react with molecular oxygen to form superoxides

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and Waterham, H.R

Actinomycetes play several roles in the soil including OM cycling, ammonium fixation, humus formation and decomposition, decomposition of recalcitrant and resistant organic polymers (e.g., lignin, cellulose and chitin), soil aggregate formation and stabilization, solubilization of phosphates, suppression of soil pathogens and pesticide degradation [5, 228, 230,231,232]