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For each eligible study, two authors (MM and AN) independently extracted data, which was then reviewed by a third author (JV) using a piloted spreadsheet, in accordance with Cochrane Collaboration guidelines ( Where relevant data were missing, attempts were made to contact corresponding authors

The aim of MS treatment is the prevention of long-term functional deterioration by preventing flares

This service is commonly performed in various healthcare settings, including hospitals, clinics, and outpatient facilities

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Shock unresponsive to conventional therapy if adrenocortical insufficiency exists or is suspected