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2009) and N = 13 (Edden et al

Increase in serum choline levels predicts for improved progression-free survival (PFS) in patients with advanced cancers receiving pembrolizumab

In contrast, the detrimental effect of mitophagy mostly occurs in scenarios of excessive activation or abnormal regulation: when cells encounter sustained and severe pathological stress (such as severe ischemia and severe inflammation), mitophagy is abnormally activated, which excessively degrades functionally normal mitochondria, leading to disorders of cellular energy metabolism, insufficient ATP synthesis, and simultaneous disruption of the normal proliferation and renewal balance of mitochondria in cells

mansoni cercariae shed from Biomphalaria glabrata for 23 h after exposure to light, with mechanical transformation performed as described [36]

doi: 10.1039/d0fo02778b 141 PerryRJPengLBarryNAClineGWZhangDCardoneRLet al