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The drug development partners had been seeking approval for patritumab deruxtecan, an antibody-drug conjugate (ADC), to treat patients with advanced or metastatic NSCLC bearing certain genetic mutations

Org Geochem 20:867900

The results are consistently positive and the mechanistic data is compelling, but as of 2026 there are no completed Phase 3 human randomized controlled trials

Hirunpattarasilp C, Attwell D, Freitas F

Companies must also provide market research demonstrating the technology is a viable solution and obtain written confirmation from a Program Acquisition Executive who plans to secure follow-on funding and confirming operational priority