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Together with our findings that tideglusib protected dopaminergic neurons from aSyn-induced toxicity, it would be worthwhile to continue with clinical trials of tideglusib in PD

33 :e13885 24

J.HuC.et al

These proteases exist as inactive zymogens and require proteolytic cleavage to become enzymatically active

The emerging diversity of the lysine acylation landscape prompted us to investigate the function and mechanism of these novel HPTMs in health and disease