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MT2 modification monitored by ESIMS In the second part of the study, mass spectrometry was used to monitor MT2 modification and the dissociation of Zn(II) from fully Zn(II)-loaded protein

Most of the members of the SLC group are located in the cell membrane

Recent changes in therapeutic approaches and association with outcomes among patients with secondary hyperparathyroidism on chronic hemodialysis: the DOPPS study

The need for glutamine is particularly urgent in highly proliferating cells such as cancer cells and diseased blood vessel cells ( Dysfunction of Glutamine Metabolism in Pulmonary Hypertension Until now, metabolic reprogramming and mitochondrial dysfunction have been considered as the key events, leading to the excessive proliferation and anti-apoptosis of pulmonary vascular cells in the progress of PH ( It is well known that structural and functional alterations of pulmonary arterial smooth muscle cells (PASMC) and pulmonary artery endothelial cells (PAEC) lead to remodeling of the pulmonary artery wall and increase vascular resistance

GSH via GSH peroxidases and GSH S-transferases, helps control oxidations of arachidonate, thereby decreasing lipid hydroperoxides, isoeicosanoids and eicosanoids that can be overly proinflammatory and disadvantageously apoptogenic and immunosuppressive