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Conclusion: This study emphasizes the importance of patients, caregivers, healthcare providers education on DOAC treatment importance and consequences

As to ligands, their frustrating elements are the drivers, which can exert attractive pulling or repulsive pushing interactions and anchors at the allosteric sites (Nussinov and Tsai, Reference Nussinov and Tsai2014b)

Western blot analysis was performed using purified polyclonal anti-human SOD2 rabbit IgG

Results We demonstrated that this peptide-liposome-small molecule machinery targets AML and consequently induces cell apoptosis both in vitro and in vivo through three disparate mechanisms: (I) Oridonin, as a Michael acceptor molecule, inhibits GSH function through covalent bonding, triggering an initial imbalance of oxidative stress