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RP/MRD cells also showed upregulated ROS- and oxidative stressrelated pathways by multiomics (Figure 3, B and D, and Supplemental Figure 3, B, D, and G) and increased reducing activity, including glutathione metabolism (Figure 3C and Supplemental Figure 3C), consistent with an increase in ROS generation due to enhanced OXPHOS

doi: 10.1038/nrn3531

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The original version of this article was revised: Jaccard index incorrectly had subset 1 in the numerator, and the absolute value bars were missing in the denominator