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Cost vs benefit: Given modest effect, the return may be limited compared to healthy habits (diet, sleep, sun protection)

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Its direct suppression of NF-kB, the master inflammatory transcription factor involved in psoriasis, gives it the strongest mechanistic rationale

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[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Xu X.M., Carlson B.A., Irons R., Mix H., Zhong N., Gladyshev V.N., Hatfield D.L